Facts 25/08/2025 23:17

Scientists discover that powerful side effect of Ozempic could actually reverse aging

While the news used to be dominated by headlines warning against the use of Ozempic, Mounjaro, Wegovy, and other so-called "skinny jabs," the scientific community continues its deep investigation into whether some potential benefits could outweigh the negative side effects. These drugs have been at the center of much debate, with mixed opinions about their safety and effectiveness.

With major celebrities like Oprah Winfrey and Elon Musk publicly admitting to using 'skinny jabs' as part of their transformation, it's no wonder these drugs have gained popularity. Their rise in use is not just limited to the elite and famous anymore. The public has taken a keen interest in semaglutide injections, a treatment known for its weight-loss properties. Although some have raised concerns about potential side effects such as osteoporosis, decreased libido, and the possibility of a mental health crisis, others firmly stand by them. Many have even celebrated the term 'Ozempic penis' in reference to men’s reported sexual health benefits, alongside cardiovascular improvements and a reduction in liver scarring.

But now, new research from Kentucky’s TruDiagnostic aging lab presents an intriguing idea: semaglutide injections might have the potential to reverse aging. This theory has sparked considerable excitement within the scientific community and among the general public. According to the research, semaglutide injections may go beyond merely slowing aging — they could actually reverse it.

While these findings are yet to undergo peer review, Futurism reports that scientist Varun Dwaraka argues that regular weekly doses of the semaglutide GLP-1 drug, found in Ozempic and similar treatments, could potentially dial back a person's biological age by as much as three years. It’s important to note that biological age is different from chronological age. While chronological age refers to the number of years a person has lived, biological age is a measure of how old the body actually feels. Using 'epigenetic clocks' — a tool that tracks changes in DNA methylation (the chemical signals added or removed from our DNA as we age) — Dwaraka and his team analyzed the biological age of participants.

The study focused on 184 participants suffering from HIV-associated lipohypertrophy, a condition marked by accelerated biological aging, early onset of age-related illnesses, low-grade inflammation, and metabolic dysfunction. Over the course of 32 weeks, one group received weekly GLP-1 injections, while the other group was given a placebo. At the study’s conclusion, Dwaraka revealed that the GLP-1 group, on average, had biologically "reversed" by 3.1 years. Even more remarkably, some participants showed up to five years of brain age reversal, and signs of slower aging in the heart, kidneys, and inflammatory systems were also reported.

Though Dwaraka cautioned that it’s too early to declare ‘skinny jabs’ as a miracle cure for biological aging, he acknowledged that the results were highly promising. He said, "Semaglutide may not only slow the rate of aging, but in some individuals, it may partially reverse it."

The FDA has approved semaglutide for treating type 2 diabetes and reducing the risk of kidney disease progression in adults with type 2 diabetes and chronic kidney disease. However, the agency has also issued warnings about possible side effects, such as intestinal blockages and allergic reactions, and has raised concerns about the dangers of acquiring unapproved versions of GLP-1 injections.

As the research continues, supporters and skeptics of semaglutide remain divided, with more studies needed to truly understand the full scope of its effects on aging.

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